Iron Stores Affect Absorption

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Healthy adults have total body iron of approximately 4g for men and 2.5g for women.1 While most of this iron is contained in the hemoglobin in your red blood cells, iron storage sites also contain approximately 1g in men and 0.3g in women.2

In addition to the iron you use each day, you typically lose about 1 mg or more, so it's important to make sure you eat enough iron-rich foods to give your body the iron it needs.1,2

Under normal circumstances, you might absorb 5 to 10% of the iron in your food.2 However, your body will automatically decrease absorption if you have enough iron stored away. And, if you don't have enough iron stores, your body will increase absorption.2,3

Important Safety Information

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF THE REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately.

Warning

Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient.

Precautions

Administration of Drug
  • General: Take 2 hours after meals. Do not exceed recommended dose. Discontinue use if symptoms of intolerance appear. The type of anemia and underlying cause or causes should be determined before starting therapy with Ferralet® 90 tablets. Ensure Hgb, Hct, reticulocyte count are determined before starting therapy and periodically thereafter during prolonged treatment. Periodically review therapy to determine if it needs to be continued without change or if a dose change is indicated. This product contains FD&C Yellow No. 5 (tartrazine) which may cause allergic type reactions (including bronchial asthma) in certain susceptible persons. Although the overall incidence of FD&C Yellow No. 5 (tartrazine) sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity.
  • Folic Acid: Folic acid in doses above 0.1 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations remain progressive. Pernicious anemia should be excluded before using these products since folic acid may mask the symptoms of pernicious anemia.
  • Pediatric Use: Safety and effectiveness in pediatric patients have not been established.
  • Geriatric Use: Dosing for elderly patients should be cautious. Due to the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy, dosing should start at the lower end of the dosing range.

This material is intended to provide basic information. Patients should discuss all medical advice, diagnosis, and treatment with their healthcare provider.

Please see full Prescribing Information

  1. Recommendations to prevent and control iron deficiency in the United States [Internet]. Centers for Disease Control and Prevention; 1998 Apr 3 [accessed 2008 Apr 9]. Available from: http://www.cdc.gov/mmwr/preview/mmwrhtml/00051880.htm.
  2. Barton JC. Iron deficiency. In Rakel RE, Bope ET. Conn's Current Therapy, 2008. Amsterdam, The Netherlands: Saunders/Elsevier, 385-389.
  3. Finch CA, Cook JD. Iron deficiency. American Journal of Clinical Nutrition. 1984 Mar;39(3):471-7.